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All issuesVolume 338, Issue 2IT Vendor NewsCisco

Shields Up: Guidance for Defending in the Age of AI-Enabled Attacks

Cisco, Thursday, May 14th, 2026

Cisco outlines how AI-enabled cyber attacks are evolving and provides defensive recommendations for organizations.

Cisco released guidance on defending against AI-enabled cyber attacks following their experience with Anthropic's advanced AI model Mythos. The document examines how malicious actors have already begun using AI and LLMs in attack campaigns, from social engineering to vulnerability discovery, and explains how more sophisticated AI models could lower the skill barrier for exploitation.

Cisco details how they are adapting their security practices through AI-powered vulnerability discovery, updated threat modeling, and red teaming exercises, while also contributing secure-by-default frameworks like Project CodeGuard to help organizations build more resilient systems against these emerging threats.

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